Hieronder staan de stedelijke gebieden met meer dan 100.000 inwoners in Guatemala gerangschikt op inwonertal.
Stedelijk gebied (of stedelijke agglomeratie) verwijst naar de bevolking binnen de contouren van een aaneengesloten gebied dat bewoond wordt op stedelijk dichtheidsniveau, doorgaans bestaande uit een stad en de omliggende voorsteden.
| Rang | Stedelijk Gebied | Bevolkingsschatting (2025) | Verandering in 1 jaar (t.o.v. 2024) | Landoppervlak (km²) | Dichtheid (P/Km²) | Wereldwijde rang | Prognoses (2030) | Prognoses (2050) |
|---|---|---|---|---|---|---|---|---|
| 1 | Ciudad de Guatemala (Guatemala City) | 2.837.708 | 0,69% | 458 | 6.196 | 175 | 2.954.173 | 3.316.118 |
| 2 | Quetzaltenango | 291.105 | 4,14% | 86 | 3.385 | 1.995 | 305.913 | 446.130 |
| 3 | Cobán | 229.017 | 1,81% | 24 | 9.542 | 2.564 | 250.358 | 311.962 |
| 4 | Chimaltenango | 175.556 | 0,91% | 25 | 7.022 | 3.446 | 197.199 | 253.167 |
| 5 | Flores | 146.517 | 2,71% | 26 | 5.635 | 4.155 | 161.603 | 229.534 |
| 6 | San Pedro Sacatepéquez [San Marcos] | 115.711 | 1,38% | 36 | 3.214 | 5.306 | 131.577 | 159.240 |
| 7 | Santa Lucía Cotzumalguapa | 113.604 | 0,83% | 15 | 7.574 | 5.418 | 118.598 | 151.646 |
| 8 | Escuintla | 113.313 | 0,68% | 23 | 4.927 | 5.441 | 125.553 | 151.714 |
| 9 | Totonicapán | 112.939 | 3,69% | 39 | 2.896 | 5.463 | 135.052 | 233.541 |
| 10 | Mazatenango | 111.597 | 1,04% | 19 | 5.874 | 5.535 | 119.770 | 141.974 |
| 11 | San Pedro Sacatepéquez | 109.977 | 4,7% | 24 | 4.582 | 5.614 | 153.461 | 181.463 |
| 12 | Antigua Guatemala | 107.557 | 0,73% | 25 | 4.302 | 5.744 | 111.727 | 135.535 |
| 13 | Coatepeque | 106.881 | 1,87% | 23 | 4.647 | 5.781 | 115.818 | 141.325 |
| 14 | San Pedro Carchá | 106.327 | 1,43% | 12 | 8.861 | 5.806 | 114.078 | 152.956 |
| 15 | Jalapa | 88.859 | 1,06% | 15 | 5.924 | 6.985 | 92.326 | 102.916 |
| 16 | Santa Cruz Barillas | 84.759 | 1,49% | 9 | 9.418 | 7.362 | 90.092 | 113.702 |
| 17 | Santa Cruz del Quiché | 82.596 | 0,96% | 14 | 5.900 | 7.537 | 86.727 | 131.869 |
| 18 | Chiantla | 74.699 | 2,27% | 16 | 4.669 | 8.332 | 79.222 | 92.908 |
| 19 | Sololá - Tz'olöj Ya' | 69.740 | 1,79% | 18 | 3.874 | 8.901 | 105.668 | 155.694 |
| 20 | Puerto Barrios | 67.549 | 1,04% | 18 | 3.753 | 9.168 | 71.195 | 133.529 |
| 21 | Retalhuleu | 65.454 | 0,88% | 12 | 5.455 | 9.467 | 71.734 | 115.727 |
| 22 | Grufes Sector de Mujere | 64.484 | 0,99% | 9 | 7.165 | 9.603 | 67.801 | 102.174 |
| 23 | Chiquimula | 64.291 | 0,63% | 11 | 5.845 | 9.625 | 67.979 | 75.155 |
| 24 | Poptún | 63.498 | 2,5% | 14 | 4.536 | 9.748 | 73.659 | 106.221 |
| 25 | Malacatán | 63.050 | 1,43% | 9 | 7.006 | 9.822 | 70.562 | 99.203 |
| 26 | Momostenango | 62.547 | 2,03% | 16 | 3.909 | 9.917 | 69.263 | 102.733 |
| 27 | Morales | 58.588 | 1,66% | 12 | 4.882 | 10.539 | 62.252 | 88.236 |
| 28 | Jutiapa | 57.456 | 1,33% | 13 | 4.420 | 10.724 | 60.043 | 80.490 |
| 29 | San Pedro Soloma | 57.409 | 1,99% | 13 | 4.416 | 10.735 | 61.108 | 74.417 |
| 30 | El Estor | 54.824 | 1,28% | 8 | 6.853 | 11.230 | 58.561 | 71.154 |
| 31 | Santa María Nebaj | 52.609 | – | 7 | 7.516 | 11.688 | 55.913 | 68.641 |
Bron: Verenigde Naties, Department of Economic and Social Affairs, Population Division (2025). World Urbanization Prospects: The 2025 Revision, Online Edition.