Below are the urban areas with more than 100,000 inhabitants in Guatemala ranked by population.
Urban Area (or urban agglomeration) population refers to the population contained within the contours of a contiguous territory inhabited at urban density levels, typically comprising a city and its surrounding suburban fringe.
| Rank | Urban Area | Population Estimate (2025) | 1 Year Change (over 2024) | Land Area (Km²) | Density (P/Km²) | Global Rank | Projections (2030) | Projections (2050) |
|---|---|---|---|---|---|---|---|---|
| 1 | Ciudad de Guatemala (Guatemala City) | 2,837,708 | 0.69% | 458 | 6,196 | 175 | 2,954,173 | 3,316,118 |
| 2 | Quetzaltenango | 291,105 | 4.14% | 86 | 3,385 | 1,995 | 305,913 | 446,130 |
| 3 | Cobán | 229,017 | 1.81% | 24 | 9,542 | 2,564 | 250,358 | 311,962 |
| 4 | Chimaltenango | 175,556 | 0.91% | 25 | 7,022 | 3,446 | 197,199 | 253,167 |
| 5 | Flores | 146,517 | 2.71% | 26 | 5,635 | 4,155 | 161,603 | 229,534 |
| 6 | San Pedro Sacatepéquez [San Marcos] | 115,711 | 1.38% | 36 | 3,214 | 5,306 | 131,577 | 159,240 |
| 7 | Santa Lucía Cotzumalguapa | 113,604 | 0.83% | 15 | 7,574 | 5,418 | 118,598 | 151,646 |
| 8 | Escuintla | 113,313 | 0.68% | 23 | 4,927 | 5,441 | 125,553 | 151,714 |
| 9 | Totonicapán | 112,939 | 3.69% | 39 | 2,896 | 5,463 | 135,052 | 233,541 |
| 10 | Mazatenango | 111,597 | 1.04% | 19 | 5,874 | 5,535 | 119,770 | 141,974 |
| 11 | San Pedro Sacatepéquez | 109,977 | 4.7% | 24 | 4,582 | 5,614 | 153,461 | 181,463 |
| 12 | Antigua Guatemala | 107,557 | 0.73% | 25 | 4,302 | 5,744 | 111,727 | 135,535 |
| 13 | Coatepeque | 106,881 | 1.87% | 23 | 4,647 | 5,781 | 115,818 | 141,325 |
| 14 | San Pedro Carchá | 106,327 | 1.43% | 12 | 8,861 | 5,806 | 114,078 | 152,956 |
| 15 | Jalapa | 88,859 | 1.06% | 15 | 5,924 | 6,985 | 92,326 | 102,916 |
| 16 | Santa Cruz Barillas | 84,759 | 1.49% | 9 | 9,418 | 7,362 | 90,092 | 113,702 |
| 17 | Santa Cruz del Quiché | 82,596 | 0.96% | 14 | 5,900 | 7,537 | 86,727 | 131,869 |
| 18 | Chiantla | 74,699 | 2.27% | 16 | 4,669 | 8,332 | 79,222 | 92,908 |
| 19 | Sololá - Tz'olöj Ya' | 69,740 | 1.79% | 18 | 3,874 | 8,901 | 105,668 | 155,694 |
| 20 | Puerto Barrios | 67,549 | 1.04% | 18 | 3,753 | 9,168 | 71,195 | 133,529 |
| 21 | Retalhuleu | 65,454 | 0.88% | 12 | 5,455 | 9,467 | 71,734 | 115,727 |
| 22 | Grufes Sector de Mujere | 64,484 | 0.99% | 9 | 7,165 | 9,603 | 67,801 | 102,174 |
| 23 | Chiquimula | 64,291 | 0.63% | 11 | 5,845 | 9,625 | 67,979 | 75,155 |
| 24 | Poptún | 63,498 | 2.5% | 14 | 4,536 | 9,748 | 73,659 | 106,221 |
| 25 | Malacatán | 63,050 | 1.43% | 9 | 7,006 | 9,822 | 70,562 | 99,203 |
| 26 | Momostenango | 62,547 | 2.03% | 16 | 3,909 | 9,917 | 69,263 | 102,733 |
| 27 | Morales | 58,588 | 1.66% | 12 | 4,882 | 10,539 | 62,252 | 88,236 |
| 28 | Jutiapa | 57,456 | 1.33% | 13 | 4,420 | 10,724 | 60,043 | 80,490 |
| 29 | San Pedro Soloma | 57,409 | 1.99% | 13 | 4,416 | 10,735 | 61,108 | 74,417 |
| 30 | El Estor | 54,824 | 1.28% | 8 | 6,853 | 11,230 | 58,561 | 71,154 |
| 31 | Santa María Nebaj | 52,609 | – | 7 | 7,516 | 11,688 | 55,913 | 68,641 |
Source: United Nations, Department of Economic and Social Affairs, Population Division (2025). World Urbanization Prospects: The 2025 Revision, Online Edition.