Below are the urban areas with more than 100,000 inhabitants in Panama ranked by population.
Urban Area (or urban agglomeration) population refers to the population contained within the contours of a contiguous territory inhabited at urban density levels, typically comprising a city and its surrounding suburban fringe.
| Rank | Urban Area | Population Estimate (2025) | 1 Year Change (over 2024) | Land Area (Km²) | Density (P/Km²) | Global Rank | Projections (2030) | Projections (2050) |
|---|---|---|---|---|---|---|---|---|
| 1 | Ciudad de Panamá (Panama City) | 1,527,393 | 1.66% | 280 | 5,455 | 327 | 1,591,070 | 1,822,485 |
| 2 | Arraiján | 257,136 | 1.73% | 66 | 3,896 | 2,274 | 272,252 | 338,578 |
| 3 | Colón | 187,007 | 1.48% | 53 | 3,528 | 3,229 | 201,858 | 251,935 |
| 4 | La Chorrera | 166,922 | 1.56% | 50 | 3,338 | 3,625 | 175,576 | 209,703 |
| 5 | David | 121,467 | 0.38% | 34 | 3,573 | 5,050 | 123,332 | 133,195 |
Source: United Nations, Department of Economic and Social Affairs, Population Division (2025). World Urbanization Prospects: The 2025 Revision, Online Edition.